This screen lists stocks on US OTC markets where today's or yesterday's volume was at least five times the 50-day average, ranked by how far today's volume is above its 21-day average. A sudden surge in volume means something has changed: news, earnings, an analyst call or a large investor building a position. Check the price action too: a spike on a rising price points to accumulation, on a falling price to distribution. OTC stocks trade outside the major exchanges and are often thinly traded penny stocks; the list covers US OTC stocks with at least $100,000 in average daily trading value.