This screen ranks profitable stocks on US OTC markets by price-to-earnings ratio, lowest first, and shows the 100 cheapest. A low P/E can mean the market is overlooking a company, but it can also reflect a one-time gain, a cyclical earnings peak or real business risk. Check whether earnings are sustainable, and compare the P/E with the company's own history and its industry. OTC stocks trade outside the major exchanges and are often thinly traded penny stocks; the list covers US OTC stocks with at least $100,000 in average daily trading value.