This list ranks NYSE and Nasdaq stocks by their year-to-date (YTD) price gain, the percentage change since the last close of the previous year, and shows the top 100. The YTD leaderboard is where the market's big themes of the year show up first. Penny stocks and illiquid names are excluded.
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| Symbol | Name | Industry | Sector | Exchange | Cap | Cap, mln | Last | Change | Change, % | Volume | Ytd_pct |
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| Specialty Business Services | Industrials | NASDAQ | Small | 1,036.61 |
6.11 |
0.27 | 4.62 | 414,653 |
851.71 |
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| Biotechnology | Healthcare | NASDAQ | Large | 88,519 |
221.72 |
-1.04 | -0.47 | 8,579,481 |
651.85 |
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| Biotechnology | Healthcare | NASDAQ | Small | 615 |
9.55 |
-0.73 | -7.1 | 262,097 |
572.54 |
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| Waste Management | Industrials | NASDAQ | Micro | 141.02 |
4.53 |
0.06 | 1.34 | 3,900,337 |
431.88 |
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| Medical Care Facilities | Healthcare | NYSE | Small | 1,425.57 |
84.90 |
-1.04 | -1.21 | 217,456 |
393.03 |
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| Computer Hardware | Technology | NASDAQ | Large | 163,759 |
1,150.89 |
-179.16 | -13.47 | 17,341,560 |
384.83 |
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| Biotechnology | Healthcare | NASDAQ | Large | 10,129 |
152.78 |
-20.67 | -11.92 | 3,396,478 |
381.65 |
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| Insurance Brokers | Financial Services | NASDAQ | Micro | 192.79 |
4.07 |
0.1 | 2.52 | 32,022 |
377.59 |
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| Diagnostics & Research | Healthcare | NASDAQ | Mid | 4,592.77 |
87.41 |
15.89 | 22.22 | 3,552,499 |
363.96 |
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| Medical Devices | Healthcare | NASDAQ | Small | 484.01 |
15.65 |
-1.06 | -6.34 | 596,617 |
353.62 |
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| Medical Devices | Healthcare | NASDAQ | Mid | 9,134.71 |
70.11 |
-11.44 | -14.03 | 5,184,221 |
329.86 |
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| Biotechnology | Healthcare | NASDAQ | Mid | 8,786.04 |
8.29 |
-0.45 | -5.15 | 8,908,337 |
318.69 |
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| Telecom Services | Communication Services | NASDAQ | Small | 1,778.02 |
90.67 |
-1.14 | -1.24 | 396,058 |
315.35 |
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| Biotechnology | Healthcare | NASDAQ | Micro | 145.66 |
4.53 |
-0.16 | -3.41 | 284,722 |
297.37 |
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| Oil & Gas Equipment & Services | Energy | NASDAQ | Micro | 30.74 |
1.58 |
-0.04 | -2.47 | 398,358 |
296.09 |
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| Semiconductors | Technology | NASDAQ | Mid | 6,824.21 |
67.47 |
-4.14 | -5.78 | 2,716,606 |
287.09 |
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| Biotechnology | Healthcare | NASDAQ | Mid | 5,019.09 |
14.35 |
-0.63 | -4.21 | 3,691,140 |
285.75 |
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| Medical Instruments & Supplies | Healthcare | NASDAQ | Mid | 3,879.95 |
52.24 |
-3.24 | -5.84 | 466,045 |
280.48 |
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| Biotechnology | Healthcare | NASDAQ | Mid | 3,976.06 |
12.27 |
-0.81 | -6.19 | 3,871,553 |
258.77 |
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| Biotechnology | Healthcare | NASDAQ | Mid | 6,233.41 |
99.18 |
-1.22 | -1.22 | 567,388 |
254.72 |
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| Marine Shipping | Industrials | NASDAQ | Micro | 131.86 |
44.31 |
-0.48 | -1.07 | 39,903 |
245.36 |
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| Diagnostics & Research | Healthcare | NASDAQ | Micro | 245.37 |
23.26 |
-1.46 | -5.91 | 67,148 |
242.06 |
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| Computer Hardware | Technology | NYSE | Mega | 269,775 |
424.30 |
-51.21 | -10.77 | 10,452,124 |
241.93 |
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| Semiconductor Equipment & Materials | Technology | NASDAQ | Mid | 3,610.46 |
55.06 |
-5.82 | -9.56 | 14,653,212 |
236.76 |
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| 100 matches |
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| Data as of Oct 30, 2026, updated intraday |
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