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Septerna Inc

NASDAQ • Healthcare • Biotechnology • Quote as of 10/30/2026
Septerna Inc stock price and volume chart

Company Profile

IndustryBiotechnology
SectorHealthcare
ExchangeNASDAQ
Market Capitalization2,053.79 mln
Float29.77 mln
Earnings Date11/25/2026

Piotroski F-Score

6 / 9
Solid

Beneish M-Score

115
Highly suspicious

Relative Strength

97 / 100
Top performer

Debt / Equity

0.06
Debt-free

Pre-Tax Margin

-23%
Deeply loss-making

ROE

-6.33
Negative

Business Description

Septerna is a clinical-stage biotech company focused on developing oral pill-based medicines that work through a class of cell receptors known as GPCRs. Its current pipeline targets conditions such as hypoparathyroidism, chronic hives, Graves' disease, and thyroid eye disease, with additional research underway in areas like heart health, women's health, and neurology. The company also holds a partnership with Novo Nordisk to discover and bring to market oral treatments for metabolic diseases. Founded in 2019 and based in South San Francisco, California, Septerna operates across multiple therapeutic areas with the goal of addressing diseases that currently lack effective oral treatment options.

Key Fundamentals

EPS-0.54
ROE-6.33
RPS2.21
ROIC-27.14
ROA-4.39
EBITDA, mln-21.26
EV / EBITDA-79.45
EV / EBIT-73.73
Revenue, mln98.88
EV / Revenue17.09

Quote Details

Last 44.00
Change -1.23 (-2.72%)
Open 45.00
Volume 223,349
Turnover 9,827,356
Average Volume 369,388

Financial Ratios

Pre-Tax Profit Margin-23
Leverage Ratio1.47
Current Ratio5.00
Price / Book5.21
Price / Tangible Book5.21
Price / Cash Flow18.69
Price / Free Cash Flow19.39
Debt / Equity0.06
Price / Sales20.08

Financial Strength

Altman Z-Score6.68
Piotroski F-Score 6 / 9
Beneish M-Score115
Short Ratio8.65
Short % of Float14.42

Price Performance & Relative Strength

Period Price Performance Relative Strength
1 Week 8.88% 93 / 100   
1 Month 15.64% 95 / 100   
2 Months 31.38% 95 / 100   
6 Months 86.36% 98 / 100   
1 Year 101% 97 / 100   



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